THIS IS AN ASPIRE PHARMA WEBSITE PAGE INTENDED FOR UK PATIENTS WHO HAVE BEEN PRESCRIBED COMBISAL® (SALMETEROL/FLUTICASONE)
Combisal® (salmeterol/fluticasone)
Pressurised metered dose inhaler (pMDI)
About Combisal®
Summary of Product Characteristics (SmPC) and Patient Information Leaflet (PIL)
The following links will take you to the electronic Medicines Compendium (eMC) website.
By using the links below, you will leave the Pathway Portfolio website and be re-directed to an external site. Aspire Pharma is not responsible for the content on external websites.
Combisal® 25 microgram/50 microgram per metered dose pressurised inhalation, suspension
Combisal® 25 microgram/125 microgram per metered dose pressurised inhalation, suspension
Combisal® 25 microgram/250 microgram per metered dose pressurised inhalation, suspension
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Combisal® 25 microgram/50 microgram
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Combisal® 25 microgram/125 microgram
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Combisal® 25 microgram/250 microgram
What is Asthma?
Definition
Asthma is a common lung condition that affects the smaller airways (bronchioles). Occasionally the airways narrow (constrict) causing symptoms such as wheezing, coughing, chest tightness and breathlessness.1 It often starts in childhood, although it affects people of all ages, with some people developing symptoms for the first-time during adulthood. Currently, there is no cure available, however there are many treatments that can help keep your symptoms under control and increase your quality of life.2
Did you know: About 8 million people in the UK have asthma, which is about 12 in every 100 people.1
Symptoms
The most common symptoms of asthma are wheezing, cough, breathlessness and developing a feeling of tightness in the chest.1,2 Sometimes children and adults with asthma have times when their breathing becomes more difficult.2 Depending on the severity of your condition, your symptoms can range from mild to severe. Your own symptoms can vary over time and may be different to other people’s symptoms. Each episode of symptoms may last around an hour, or persist for several weeks unless treated. 1,2
Causes
Currently the exact cause of asthma is unknown.1,2 However, people may be more likely to develop asthma if they have allergies such as eczema, hay fever or food allergies, have a family history of asthma or allergies, were born prematurely or with a low birth weight, were exposed to high levels of air pollution or cigarette smoke during childhood, experienced childhood respiratory illnesses such as bronchiolitis or croup, or are overweight.2 Asthma can also develop as a result of exposure to certain substances, such as chemicals in the workplace.2
Asthma attacks occur when certain triggers cause inflammation in the airways – this causes the muscles around the airways to squeeze, leading to a narrowing of the airways which can also become clogged with mucus.1,2
Asthma triggers
Some of the most common triggers include1:
- infections like colds and flu
- allergies such as pollen, dust mites or animals
- smoke, fumes and pollution
- medicines particularly anti-inflammatory painkillers like aspirin and ibuprofen
- emotions including stress or even laughter
- mould or damp
- exercise
Once you understand your triggers, trying to avoid them may help you control your asthma symptoms.2
Resources
By using the link below you will leave the Pathway Portfolio website and be re-directed to an external site; Aspire Pharma is not responsible for the content on external websites.
References:
- Patient: Asthma. https://patient.info/chest-lungs/asthma-leaflet (Accessed June 2026)
- NHS: Asthma. https://www.nhs.uk/conditions/asthma/ (Accessed June 2026)
MAT-UK-XLP-0051-1 | June 2026
